Platelet-rich fibrin (PRF)

Platelet-rich fibrin (PRF) is a treatment that uses your own blood to promote healing and tissue regeneration. It is a newer variation of platelet-rich plasma (PRP), and it is considered it to be an improvement.

The overall process promotes tissue repair, regeneration, and potentially improved blood flow in the treated area.

  • PRF, or Platelet-Rich Fibrin, treatment leverages your body's natural healing potential to promote tissue regeneration and rejuvenation.

    Here's a breakdown of how it works

    1. Blood Draw and Centrifugation: A small amount of your blood is extracted. This blood is then placed in a centrifuge, a machine that spins rapidly to separate different components based on weight.

    2. Isolation of Platelets and Fibrin: The centrifuge spins at a controlled, slower speed compared to PRP (Platelet-Rich Plasma) treatments. This gentler spin allows for the separation of platelets, fibrin (a clotting protein), and some white blood cells from the red blood cells and remaining plasma.

    3. Crucially No Anticoagulants: Unlike PRP, PRF preparation avoids using anticoagulants. These are medications that prevent blood clotting. By skipping anticoagulants, PRF allows a natural fibrin matrix to form within the concentrated solution.

    5. Fibrin Matrix and Growth Factors: This fibrin matrix acts as a scaffold or slow-release capsule. Platelets within the PRF are rich in growth factors, chemical messengers that tell cells to grow, repair, and regenerate.

    6. Injection and Tissue Healing: The concentrated PRF solution, containing the fibrin matrix and platelets, is then injected into the targeted area. Upon injection, the fibrin matrix provides a structural base, while the platelets gradually release their growth factors over time.

    6. Cellular Communication and Regeneration: The growth factors from the platelets act as signals, stimulating nearby cells like fibroblasts and stem cells. These stimulated cells increase collagen production, a protein essential for skin structure and wound healing. The overall process promotes tissue repair, regeneration, and potentially improved blood flow in the treated area.

  • PRF (platelet-rich fibrin) offers a range of potential benefits for tissue healing and rejuvenation.

    Here's a breakdown of some key advantages

    Skin Rejuvenation


    Reduced Wrinkles and Fine Lines: By stimulating collagen production, PRF can help diminish the appearance of wrinkles and fine lines, promoting smoother skin.
    Improved Skin Texture and Tone: The treatment can enhance skin texture and tone by encouraging cell growth and renewal.
    Increased Hydration and Elasticity: PRF may improve skin hydration and elasticity, giving it a more youthful appearance.

    Other Potential Benefits

    Hair Growth: PRF injections in the scalp may promote hair growth and improve hair quality by stimulating the hair follicles.

    PRF Advantages Compared to PRP (Platelet-Rich Plasma)

    Sustained Growth Factor Release: The fibrin matrix in PRF allows for a slower, more sustained release of growth factors compared to PRP, potentially leading to longer-lasting results.
    Volumizing Effect: The fibrin matrix can also provide some initial volume correction, making PRF suitable for treating deeper wrinkles or acne scars.

  • The ideal patient for PRF treatment generally falls into one (or more) of these categories:

    Individuals Seeking Improved Skin Quality

    -Those with fine lines and wrinkles who want a natural approach to rejuvenation.
    -People with uneven skin texture or tone looking for improvement.
    -Those concerned about loss of skin elasticity or hydration.

    Patients with Injuries or Wounds

    -Individuals wanting to promote faster healing of wounds or surgical incisions.
    -People seeking improved tissue regeneration after injuries.


    Hair Loss Concerns

    Men or women with hair thinning or androgenic alopecia (genetic hair loss) who desire natural hair growth stimulation.

  • The treatment itself takes roughly an hour and a half.

    Here's a breakdown of the timeline of the results

    Right after treatment: You might see some initial volume correction due to the fibrin matrix.
    1-3 weeks: The initial volume boost from the fibrin gradually subsides.
    3-4 months: Long-term benefits like improved skin texture and collagen production become more noticeable.
    6-12 months: The regenerative effects of PRF are expected to last within this range.


    Factors Affecting Longevity

    Individual factors: Age, genetics, and overall health can influence how long the results last.
    Treatment area: The treated areas specific needs and the severity of the condition can play a role.
    Number of treatments: Typically, a series of PRF treatments spaced several weeks apart is recommended for optimal results. This can help establish a foundation for longer-lasting effects.
    Maintenance treatments: Some individuals opt for periodic maintenance treatments to prolong the benefits.

  • Following proper aftercare instructions is crucial for optimizing healing and results after PRF treatment.

    Here's a breakdown of some key aftercare guidelines

    General Measures:
    Minimize Touching: Avoid touching or rubbing the treated area for at least 8 hours after the procedure. This helps prevent irritation and infection.
    Keep Head Elevated: If possible, try to keep your head elevated above your heart for the first 4 hours following treatment. This can minimize swelling.
    Avoid Exercise: Refrain from strenuous exercise or activities that significantly elevate your blood pressure for 24-48 hours after the procedure.
    Sun Protection: Be diligent about sun protection. Avoid direct sunlight and wear sunscreen with SPF 30 or higher for at least a week after treatment. Sun exposure can hinder healing and worsen discoloration.


    Wound Care (if applicable):
    No Washing: Don't wash or shower for at least 6 hours after the procedure. This allows the injection site to heal properly.
    Gentle Cleansing: Once the initial waiting period is over, cleanse the treated area gently with a fragrance-free cleanser as instructed by your doctor.


    Products to Avoid:
    Skip Harsh Products: Avoid using harsh skincare products, scrubs, or retinoids for at least 3 days after treatment. These can irritate the sensitive injection sites.
    Hold Off on Makeup: Don't apply makeup to the treated area for at least 6 hours after the procedure.
    No Blood Thinners: Avoid blood thinners and NSAIDs (nonsteroidal anti-inflammatory drugs) like ibuprofen or aspirin for 2 weeks following treatment. These can increase the risk of bruising.


    Pain Management:
    Tylenol is Okay: If you experience discomfort or soreness, you can take acetaminophen (Tylenol) for pain relief, following the recommended dosage on the label.

    Additional Tips:
    Apply Ice (with Caution): You can apply ice packs wrapped in a thin cloth to the treated area for 20-30 minute intervals to reduce swelling. However, avoid direct application of ice to the skin.
    Stay Hydrated: Drink plenty of water to facilitate healing and flush out any potential toxins.
    Listen to Your Body: If you experience any unusual redness, swelling, or pain that worsens over time, contact your doctor immediately.

  • A series of PRF is recommended and following with a skincare routine based around your specific goals is ideal.

    Having a monthly age defying facial, chemical peel or microneedling for optimum results.

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